2(1H)-Pentalenone, 5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]hexahydro-4-(hydroxymethyl)-, (3aS,4S,5R,6aR)- - Names and Identifiers
Name | (5R,6S)-5-(tert-butyldimethylsilyloxy)-6-(hydroxymethyl)-hexahydropentalen-2(1H)-one
|
Synonyms | (5R,6S)-5-(tert-butyldimethylsilyloxy)-6-(hydroxymethyl)-hexahydropentalen-2(1H)-one (3aS,4S,5R,6aR)-5-((tert-Butyldimethylsilyl)oxy)-4-(hydroxymethyl)hexahydropentalen-2(1H)-one 5-[[(1,1-DiMethylethyl)diMethylsilyl]oxy]hexahydro-4-(hydroxyMethyl)-(3aS,4S,5R,6aR)-2(1H)-pentalenone 2(1H)-Pentalenone, 5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]hexahydro-4-(hydroxymethyl)-, (3aS,4S,5R,6aR)-
|
CAS | 871095-04-4
|
2(1H)-Pentalenone, 5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]hexahydro-4-(hydroxymethyl)-, (3aS,4S,5R,6aR)- - Physico-chemical Properties
Molecular Formula | C15H28O3Si
|
Molar Mass | 284.47 |
Density | 1.02±0.1 g/cm3(Predicted) |
Boling Point | 350.9±27.0 °C(Predicted) |
pKa | 14.90±0.10(Predicted) |
2(1H)-Pentalenone, 5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]hexahydro-4-(hydroxymethyl)-, (3aS,4S,5R,6aR)- - Introduction
(5R,6S)-5-(tert-butyldimethylsilyloxy)-6-(hydroxymethyl)-hexahydropentalen-2(1H)-one is an organic compound commonly known by the abbreviation TBDMSC. This compound has the following properties and uses:
Nature:
-Appearance: Colorless liquid or solid
-Molecular formula: C15H30O3Si
-Molecular weight: 298.49g/mol
-Solubility: Soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane, almost insoluble in water
-Melting point: about 30-35°C
-Boiling point: about 140-150°C
Use:
- TBDMSC is commonly used as a protecting group compound in organic synthesis to protect the hydroxyl (OH) functional group to prevent non-specific reactions during the reaction.
-It can be used as a stable protecting group in the process of synthesizing complex organic molecules, and can be removed by appropriate conditions when needed.
Preparation Method:
- TBDMSC can be prepared by reacting 1,1-dimethylethyl methyl ether with (t-Bu)2MeSiOH under basic conditions. This reaction can take place at ambient temperature and generally does not require much reaction time.
Safety Information:
- TBDMSC is a flammable compound and should be kept away from open flames and high temperatures.
-When using TBDMSC, take necessary safety measures, such as wearing appropriate protective gloves, eye protection and protective clothing.
-It should be operated in a well-ventilated environment, avoiding inhalation or contact with skin and eyes.
-If inhaled or inadvertently exposed to the compound, immediately remove from the source, rinse with water, and seek medical help.
Last Update:2024-04-10 22:29:15